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Laurent Brochard Selected Research

Noninvasive Ventilation

1/2024Extracorporeal Carbon Dioxide Removal to Avoid Invasive Ventilation During Exacerbations of Chronic Obstructive Pulmonary Disease: VENT-AVOID Trial - A Randomized Clinical Trial.
1/2024Noninvasive Ventilation Before Intubation and Mortality in Patients Receiving Extracorporeal Membrane Oxygenation for COVID-19: An Analysis of the Extracorporeal Life Support Organization Registry.
11/2020High-Flow Nasal Cannula Compared With Conventional Oxygen Therapy or Noninvasive Ventilation Immediately Postextubation: A Systematic Review and Meta-Analysis.
10/2019Effects of high-flow nasal cannula and non-invasive ventilation on inspiratory effort in hypercapnic patients with chronic obstructive pulmonary disease: a preliminary study.
12/2018Beyond the guidelines for non-invasive ventilation in acute respiratory failure: implications for practice.
9/2018High-flow nasal oxygen versus noninvasive ventilation in adult patients with cystic fibrosis: a randomized crossover physiological study.
1/2018Obstructive sleep apnea in patients surviving acute hypercapnic respiratory failure is best predicted by static hyperinflation.
1/2018Predictors of Intubation in Patients With Acute Hypoxemic Respiratory Failure Treated With a Noninvasive Oxygenation Strategy.
1/2017Official ERS/ATS clinical practice guidelines: noninvasive ventilation for acute respiratory failure.
1/2017Noninvasive Ventilation of Patients with Acute Respiratory Distress Syndrome. Insights from the LUNG SAFE Study.
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Laurent Brochard Research Topics

Disease

53Respiratory Insufficiency (Respiratory Failure)
05/2024 - 08/2002
50Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome)
03/2024 - 07/2002
35Critical Illness (Critically Ill)
03/2024 - 03/2003
18Lung Injury
11/2023 - 09/2002
17Chronic Obstructive Pulmonary Disease (COPD)
01/2024 - 04/2003
17Acute Lung Injury
01/2023 - 07/2002
15Hypoxia (Hypoxemia)
09/2023 - 06/2009
13COVID-19
01/2024 - 01/2020
11Infections
01/2022 - 07/2002
9Ventilator-Induced Lung Injury
03/2024 - 02/2013
8Pneumonia (Pneumonitis)
12/2023 - 01/2003
8Pulmonary Edema
01/2018 - 09/2002
7Shock
10/2020 - 11/2003
7Patient-Ventilator Asynchrony
09/2016 - 10/2006
7Acute Kidney Injury (Acute Renal Failure)
10/2013 - 04/2004
6Sepsis (Septicemia)
12/2023 - 03/2005
6Hypercapnia
02/2017 - 02/2008
5Cross Infection (Nosocomial Infection)
04/2016 - 02/2002
4Dyspnea (Shortness of Breath)
01/2022 - 11/2005
4Delirium
01/2020 - 02/2010
4Body Weight (Weight, Body)
01/2018 - 04/2002
3Acidosis
09/2023 - 02/2017
3Inflammation (Inflammations)
01/2022 - 03/2006
3Fatigue
01/2022 - 11/2011
3Muscle Weakness
01/2017 - 10/2009
3Neoplasms (Cancer)
12/2016 - 09/2002
3Human Influenza (Influenza)
05/2016 - 05/2011
3Lung Diseases (Lung Disease)
02/2016 - 08/2010
3Renal Insufficiency (Renal Failure)
12/2012 - 12/2003
3Fibrosis (Cirrhosis)
12/2004 - 05/2003
2Atrophy
02/2024 - 10/2020
2Brain Injuries (Brain Injury)
12/2023 - 07/2002
2Respiratory Acidosis
01/2022 - 01/2017
2Septic Shock (Toxic Shock Syndrome)
01/2022 - 05/2012
2Pulmonary Atelectasis
12/2020 - 12/2006
2Edema (Dropsy)
01/2020 - 09/2002
2Out-of-Hospital Cardiac Arrest
01/2018 - 06/2006
2Ventilator-Associated Pneumonia
07/2014 - 11/2005
2Paralysis (Palsy)
05/2013 - 09/2006
2Obstructive Lung Diseases (Obstructive Lung Disease)
10/2012 - 08/2010
2Pulmonary Hypertension
09/2010 - 03/2008
2Acute Chest Syndrome
08/2010 - 03/2008
2Sickle Cell Anemia (Hemoglobin S Disease)
08/2010 - 12/2003
2Pain (Aches)
08/2010 - 12/2003
2Bacterial Pneumonia
08/2004 - 09/2002
2Neutropenia
01/2003 - 09/2002
1Wounds and Injuries (Trauma)
12/2023
1Heart Diseases (Heart Disease)
12/2023
1Cough
01/2023

Drug/Important Bio-Agent (IBA)

30Oxygen (Dioxygen)IBA
03/2024 - 01/2002
7Surface-Active Agents (Surfactants)IBA
01/2022 - 03/2006
5Carbon DioxideIBA
01/2024 - 02/2006
5GasesIBA
11/2023 - 11/2005
5Biomarkers (Surrogate Marker)IBA
01/2023 - 03/2006
5Colloids (Colloid)IBA
09/2012 - 12/2004
5Granulocyte Colony-Stimulating Factor (G-CSF)IBA
05/2003 - 09/2002
4Lidocaine (Xylocaine)FDA LinkGeneric
01/2022 - 09/2002
3Interleukin-6 (Interleukin 6)IBA
01/2022 - 01/2018
3Hypnotics and Sedatives (Sedatives)IBA
01/2020 - 11/2015
3HeliumIBA
01/2017 - 01/2010
3Anti-Bacterial Agents (Antibiotics)IBA
05/2016 - 01/2010
3Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
03/2006 - 09/2002
2Neuromuscular Blocking AgentsIBA
09/2023 - 07/2021
2Fentanyl (Sublimaze)FDA LinkGeneric
09/2023 - 09/2006
2Bronchodilator Agents (Bronchodilators)IBA
08/2023 - 10/2011
2Adrenal Cortex Hormones (Corticosteroids)IBA
10/2020 - 05/2011
2Hydrocortisone (Cortisol)FDA LinkGeneric
10/2020 - 11/2012
2Proteins (Proteins, Gene)FDA Link
03/2019 - 09/2002
2Pancreatic Elastase (Elastase)IBA
01/2018 - 08/2004
2AerosolsIBA
02/2016 - 10/2011
2NitrogenIBA
06/2015 - 01/2011
2SteroidsIBA
03/2014 - 05/2011
2Bleomycin (Blenoxane)FDA LinkGeneric
08/2004 - 05/2003
2EndotoxinsIBA
08/2004 - 01/2003
2Peroxidase (Myeloperoxidase)IBA
05/2003 - 09/2002
2Interleukin-1beta (Interleukin 1 beta)IBA
01/2003 - 09/2002
2Cyclophosphamide (Cytoxan)FDA LinkGeneric
01/2003 - 09/2002
1Lactic Acid (Lactate)FDA LinkGeneric
11/2023
1Albuterol (Salbutamol)FDA LinkGeneric
08/2023
1Claudin-5IBA
01/2023

Therapy/Procedure

74Artificial Respiration (Mechanical Ventilation)
05/2024 - 01/2002
40Noninvasive Ventilation
01/2024 - 08/2002
28Positive-Pressure Respiration (Positive End-Expiratory Pressure)
03/2024 - 04/2002
25Therapeutics
08/2023 - 09/2002
20Mechanical Ventilators (Ventilator)
01/2024 - 04/2004
13Critical Care (Surgical Intensive Care)
01/2022 - 03/2005
11Extracorporeal Membrane Oxygenation
01/2024 - 02/2013
10Cannula
08/2023 - 06/2015
7Length of Stay
01/2022 - 04/2004
4Humidifiers
01/2021 - 11/2005
3Continuous Positive Airway Pressure
01/2024 - 11/2005
3Catheters
03/2022 - 11/2003
3Transplantation
09/2021 - 08/2011
3Resuscitation
12/2013 - 12/2008
2Deep Sedation
01/2022 - 09/2006
2Tracheostomy
01/2020 - 05/2003
2Interactive Ventilatory Support
03/2016 - 11/2011
2Drug Therapy (Chemotherapy)
01/2003 - 09/2002
1Anesthesia
01/2024
1Nebulizers and Vaporizers (Inhaler)
08/2023